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HALO: Fused Core Particle columns provide an alternative to UPLC Minimize

The ability of HALO to generate hyper-fast separations comes from their small particle size (2.7 µm) and from the unique Fused-Core particle technology that creates a 0.5 µm porous shell fused to a solid core particle. As mobile phase flow rate is increased to speed-up a separation, the slow mass transfer of solute molecules inside the particles limits resolving power. Fused-Core particle technology addresses this limitation by providing an incredibly small path (0.5 µm) for diffusion of solutes into and out of the stationary phase, thereby reducing the time solute molecules spend inside the particles and minimizing a major barrier to fast chromatographic separations.


 

Fused-Core® particle technology produces hyper-fast columns that can be used on practically all HPLC systems.  Columns packed with stationary phases smaller than 2 µm often require pressures in excess of what is achievable with typical HPLC instrumentation. Using a HALO column does not require an expensive ultra-high pressure instrumentation, and new laboratory protocols do not have to be developed. HALO columns can turn almost any HPLC system into a high speed workhorse.

Halo columns are available in 75, 100, 200, and 300 micron ID in multiple lengths.  They are also available in the Magic Bullet columns for ultra-fast HTS applications.

The ability of HALO to generate hyper-fast separations comes from their small particle size (2.7 µm) and from the unique Fused-Core particle technology that creates a 0.5 µm porous shell fused to a solid core particle. As mobile phase flow rate is increased to speed-up a separation, the slow mass transfer of solute molecules inside the particles limits resolving power. Fused-Core particle technology addresses this limitation by providing an incredibly small path (0.5 µm) for diffusion of solutes into and out of the stationary phase, thereby reducing the time solute molecules spend inside the particles and minimizing a major barrier to fast chromatographic separations.


 

Fused-Core® particle technology produces hyper-fast columns that can be used on practically all HPLC systems.  Columns packed with stationary phases smaller than 2 µm often require pressures in excess of what is achievable with typical HPLC instrumentation. Using a HALO column does not require an expensive ultra-high pressure instrumentation, and new laboratory protocols do not have to be developed. HALO columns can turn almost any HPLC system into a high speed workhorse.

Halo columns are available in 75, 100, 200, and 300 micron ID in multiple lengths.  They are also available in the Magic Bullet columns for ultra-fast HTS applications.


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